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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Sigma non-opioid intracellular receptor 1 | ||
| Ligand | BDBM50037134 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_594980 (CHEMBL1039838) | ||
| Ki | 201±n/a nM | ||
| Citation |  Hsin, LW; Chang, LT; Rothman, RB; Dersch, CM; Fishback, JA; Matsumoto, RR Synthesis and opioid activity of enantiomeric N-substituted 2,3,4,4a,5,6,7,7a-octahydro-1H-benzofuro[3,2-e]isoquinolines. J Med Chem53:1392-6 (2010) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Sigma non-opioid intracellular receptor 1 | |||
| Name: | Sigma non-opioid intracellular receptor 1 | ||
| Synonyms: | Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1 | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 25266.54 | ||
| Organism: | RAT | ||
| Description: | Q9R0C9 | ||
| Residue: | 223 | ||
| Sequence: |
| ||
| BDBM50037134 | |||
| n/a | |||
| Name | BDBM50037134 | ||
| Synonyms: | (+)-trans-3-Cyclopropylmethyl-2,3,4,4aalpha,5,6,7,7aalpha-octahydro-1H-benzo[4,5]furo[3,2-e]isoquinolin-9-ol | (+/-)-trans-3-Cyclopropylmethyl-2,3,4,4aalpha,5,6,7,7aalpha-octahydro-1H-benzo[4,5]furo[3,2-e]isoquinolin-9-ol | (-)-trans-3-Cyclopropylmethyl-2,3,4,4aalpha,5,6,7,7aalpha-octahydro-1H-benzo[4,5]furo[3,2-e]isoquinolin-9-ol | (4aR,7aS,12bS)-3-Cyclopropylmethyl-2,3,4,4a,5,6,7,7a-octahydro-1H-8-oxa-3-aza-benzo[d]fluoren-9-ol | CHEMBL104042 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C19H25NO2 | ||
| Mol. Mass. | 299.4073 | ||
| SMILES | Oc1cccc2c1O[C@H]1CCC[C@H]3CN(CC4CC4)CC[C@]213 | ||
| Structure | 
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