| Reaction Details |
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 | Report a problem with these data |
| Target | Glycine receptor subunit alpha-1 |
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| Ligand | BDBM50304335 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_606508 (CHEMBL1065459) |
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| IC50 | 11.48±n/a nM |
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| Citation |  Maksay, G; Vincze, Z; Nemes, P Synthesis of heteroaromatic tropeines and heterogeneous binding to glycine receptors. Bioorg Med Chem17:6872-8 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glycine receptor subunit alpha-1 |
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| Name: | Glycine receptor subunit alpha-1 |
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| Synonyms: | GLRA1_RAT | Glra1 | Glycine receptor alpha-1 chain | Glycine receptor subunit alpha-1 | Glycine, non-strychnine | Glycine, strychnine | Glyr |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 52629.37 |
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| Organism: | RAT |
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| Description: | Glycine, non-strychnine 0 RAT::P07727 |
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| Residue: | 457 |
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| Sequence: | MYSFNTLRFYLWETIVFFSLAASKEADAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNF
KGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDS
IWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTC
IMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEA
RFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRA
SLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKSPMLNLF
QDDEGGEGRFNFSAYGMGPACLQAKDGISVKGANNNNTTNPAPAPSKSPEEMRKLFIQRA
KKIDKISRIGFPMAFLIFNMFYWIIYKIVRREDVHNK
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| BDBM50304335 |
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| n/a |
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| Name | BDBM50304335 |
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| Synonyms: | 3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-nortropane | CHEMBL608710 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H20N2O2 |
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| Mol. Mass. | 284.3529 |
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| SMILES | Cn1c(cc2ccccc12)C(=O)OC1C[C@H]2CC[C@H](C1)N2 |r,TLB:12:13:20:16.17| |
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| Structure | 
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