| Reaction Details |
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 | Report a problem with these data |
| Target | Hepatocyte nuclear factor 4-alpha |
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| Ligand | BDBM50304340 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_606516 (CHEMBL1065467) |
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| EC50 | 2090±n/a nM |
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| Citation |  Le Guével, R; Oger, F; Lecorgne, A; Dudasova, Z; Chevance, S; Bondon, A; Barath, P; Simonneaux, G; Salbert, G Identification of small molecule regulators of the nuclear receptor HNF4alpha based on naphthofuran scaffolds. Bioorg Med Chem17:7021-30 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Hepatocyte nuclear factor 4-alpha |
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| Name: | Hepatocyte nuclear factor 4-alpha |
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| Synonyms: | HNF4 | HNF4A | HNF4A_HUMAN | NR2A1 | TCF14 | hepatocyte nuclear factor 4-alpha isoform b |
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| Type: | PROTEIN |
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| Mol. Mass.: | 52790.24 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_606516 |
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| Residue: | 474 |
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| Sequence: | MRLSKTLVDMDMADYSAALDPAYTTLEFENVQVLTMGNDTSPSEGTNLNAPNSLGVSALC
AICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRYCRLKKC
FRAGMKKEAVQNERDRISTRRSSYEDSSLPSINALLQAEVLSRQITSPVSGINGDIRAKK
IASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFK
DVLLLGNDYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAK
GLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFIKL
FGMAKIDNLLQEMLLGGSPSDAPHAHHPLHPHLMQEHMGTNVIVANTMPTHLSNGQMCEW
PRPRGQAATPETPQPSPPGGSGSEPYKLLPGAVATIVKPLSAIPQPTITKQEVI
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| BDBM50304340 |
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| n/a |
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| Name | BDBM50304340 |
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| Synonyms: | 2-Nitro-naphtho[2,1-b]furan | 2-nitronaphtho[2,1-b]furan | CHEMBL7174 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H7NO3 |
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| Mol. Mass. | 213.1889 |
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| SMILES | [O-][N+](=O)c1cc2c(ccc3ccccc23)o1 |
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| Structure | 
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