| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Lysophosphatidic acid receptor 1 |
|---|
| Ligand | BDBM50304581 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_605126 (CHEMBL1064669) |
|---|
| Ki | 311±n/a nM |
|---|
| Citation |  Fells, JI; Tsukahara, R; Liu, J; Tigyi, G; Parrill, AL Structure-based drug design identifies novel LPA3 antagonists. Bioorg Med Chem17:7457-64 (2009) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Lysophosphatidic acid receptor 1 |
|---|
| Name: | Lysophosphatidic acid receptor 1 |
|---|
| Synonyms: | EDG2 | LPA receptor 1 | LPA-1 | LPA1 | LPAR1 | LPAR1_HUMAN | Lysophosphatidic acid receptor 1 (LPA1) | Lysophosphatidic acid receptor Edg-2 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 41120.55 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q92633 |
|---|
| Residue: | 364 |
|---|
| Sequence: | MAAISTSIPVISQPQFTAMNEPQCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVC
IFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVST
WLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGA
IPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMS
RHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLA
EFNSAMNPIIYSYRDKEMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILAGVHSND
HSVV
|
|
|
|---|
| BDBM50304581 |
|---|
| n/a |
|---|
| Name | BDBM50304581 |
|---|
| Synonyms: | 2-(1,3-dioxo-5-(p-tolyloxy)isoindolin-2-yl)acetic acid | CHEMBL607806 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H13NO5 |
|---|
| Mol. Mass. | 311.2888 |
|---|
| SMILES | Cc1ccc(Oc2ccc3C(=O)N(CC(O)=O)C(=O)c3c2)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
