| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Lysophosphatidic acid receptor 3 |
|---|
| Ligand | BDBM50271765 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_605121 (CHEMBL1073935) |
|---|
| IC50 | 1230±n/a nM |
|---|
| Citation |  Fells, JI; Tsukahara, R; Liu, J; Tigyi, G; Parrill, AL Structure-based drug design identifies novel LPA3 antagonists. Bioorg Med Chem17:7457-64 (2009) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Lysophosphatidic acid receptor 3 |
|---|
| Name: | Lysophosphatidic acid receptor 3 |
|---|
| Synonyms: | EDG7 | LPA3 | LPAR3 | LPAR3_HUMAN | Lysophosphatidic acid receptor 1/3 | Lysophosphatidic acid receptor 3 (LPAR3) | Lysophosphatidic acid receptor Edg-7 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 40149.72 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q9UBY5 |
|---|
| Residue: | 353 |
|---|
| Sequence: | MNECHYDKHMDFFYNRSNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRK
FHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNL
LVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLA
PIYSRSYLVFWTVSNLMAFLIMVVVYLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLMKT
VMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDM
YGTMKKMICCFSQENPERRPSRIPSTVLSRSDTGSQYIEDSISQGAVCNKSTS
|
|
|
|---|
| BDBM50271765 |
|---|
| n/a |
|---|
| Name | BDBM50271765 |
|---|
| Synonyms: | 3-(4-{3-[4-(3-Carboxy-acryloylamino)-phenoxy]-phenoxy}-phenylcarbamoyl)-acrylic acid | 4,4'-(4,4'-(1,3-phenylenebis(oxy))bis(4,1-phenylene))bis(azanediyl)bis(4-oxobut-2-enoic acid) | CHEMBL482498 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H20N2O8 |
|---|
| Mol. Mass. | 488.4456 |
|---|
| SMILES | OC(=O)\C=C\C(=O)Nc1ccc(Oc2cccc(Oc3ccc(NC(=O)\C=C\C(O)=O)cc3)c2)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
