| Reaction Details |
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 | Report a problem with these data |
| Target | Tissue alpha-L-fucosidase |
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| Ligand | BDBM50304627 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_604167 (CHEMBL1039761) |
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| Ki | 1±n/a nM |
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| Citation |  Pearson, MS; Floquet, N; Bello, C; Vogel, P; Plantier-Royon, R; Szymoniak, J; Bertus, P; Behr, JB The spirocyclopropyl moiety as a methyl surrogate in the structure of l-fucosidase and l-rhamnosidase inhibitors. Bioorg Med Chem17:8020-6 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Tissue alpha-L-fucosidase |
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| Name: | Tissue alpha-L-fucosidase |
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| Synonyms: | Alpha-L-fucosidase 1 | FUCA1 | FUCO_BOVIN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 54093.12 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_335897 |
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| Residue: | 468 |
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| Sequence: | MRSWVVGARLLLLLQLVLVLGAVRLPPCTDPRHCTDPPRYTPDWPSLDSRPLPAWFDEAK
FGVFVHWGVFSVPAWGSEWFWWHWQGEKLPQYESFMKENYPPDFSYADFGPRFTARFFNP
DSWADLFKAAGAKYVVLTTKHHEGYTNWPSPVSWNWNSKDVGPHRDLVGELGTAIRKRNI
RYGLYHSLLEWFHPLYLRDKKNGFKTQYFVNAKTMPELYDLVNRYKPDLIWSDGEWECPD
TYWNSTDFLAWLYNDSPVKDEVVVNDRWGQNCSCHHGGYYNCKDKFQPETLPDHKWEMCT
SIDQRSWGYRRDMEMADITNESTIISELVQTVSLGGNYLLNVGPTKDGLIVPIFQERLLA
VGKWLSINGEAIYASKPWRVQSEKNSVWYTSKGLAVYAILLHWPEYGILSLISPIATSTT
KVTMLGIQKDLKWSLNPSGKGLLVFLPQLPPAALPTEFAWTIKLTGVK
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| BDBM50304627 |
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| n/a |
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| Name | BDBM50304627 |
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| Synonyms: | (2S,3S,4R,5R,6S)-6-methylpiperidine-2,3,4,5-tetraol | CHEMBL596048 |
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| Type | Small organic molecule |
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| Emp. Form. | C6H13NO4 |
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| Mol. Mass. | 163.1717 |
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| SMILES | C[C@@H]1N[C@@H](O)[C@@H](O)[C@H](O)[C@@H]1O |r| |
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| Structure | 
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