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TargetAdenosine receptor A3
LigandBDBM50304631
Substrate/Competitorn/a
Meas. Tech.ChEMBL_604437
Ki 0.97±n/a nM
Citation Choi WJLee HWKim HOChinn MGao ZGPatel AJacobson KAMoon HRJung YHJeong LS Design and synthesis of N(6)-substituted-4'-thioadenosine-5'-uronamides as potent and selective human A(3) adenosine receptor agonists. Bioorg Med Chem 17:8003-11 (2009) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Adenosine receptor A3
Name:Adenosine receptor
Synonyms:A3 adenosine receptor (hA3) | Adenosine A3 receptor (A3AR)
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:36197.32
Organism:Homo sapiens (Human)
Description:P0DMS8
Residue:318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA
LSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC
VVCHPSDSLDTSIEKNSE
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  Blast E-value cutoff:
BDBM50304631
n/a
NameBDBM50304631
Synonyms:9-(5'-Cyclopentylaminocarbonyl-4'-thio-beta-D-ribofuranosyl)-N6-methyladenine | CHEMBL595569
TypeSmall organic molecule
Emp. Form.C16H22N6O3S
Mol. Mass.378.449
SMILESCNc1ncnc2n(cnc12)[C@@H]1S[C@@H]([C@@H](O)[C@H]1O)C(=O)NC1CCCC1 |r|
Structure
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