| Reaction Details |
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 | Report a problem with these data |
| Target | Papain |
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| Ligand | BDBM50304797 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_606254 (CHEMBL1069944) |
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| Ki | 10±n/a nM |
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| Citation |  Löser, R; Gut, J; Rosenthal, PJ; Frizler, M; Gütschow, M; Andrews, KT Antimalarial activity of azadipeptide nitriles. Bioorg Med Chem Lett20:252-5 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Papain |
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| Name: | Papain |
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| Synonyms: | Allergen=Car p 1 | PAPA1_CARPA | PPI | Papaya proteinase I |
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| Type: | Enzyme |
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| Mol. Mass.: | 38923.01 |
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| Organism: | Carica papaya |
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| Description: | Papain was purchased from Sigma, Germany. |
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| Residue: | 345 |
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| Sequence: | MAMIPSISKLLFVAICLFVYMGLSFGDFSIVGYSQNDLTSTERLIQLFESWMLKHNKIYK
NIDEKIYRFEIFKDNLKYIDETNKKNNSYWLGLNVFADMSNDEFKEKYTGSIAGNYTTTE
LSYEEVLNDGDVNIPEYVDWRQKGAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLNE
YSEQELLDCDRRSYGCNGGYPWSALQLVAQYGIHYRNTYPYEGVQRYCRSREKGPYAAKT
DGVRQVQPYNEGALLYSIANQPVSVVLEAAGKDFQLYRGGIFVGPCGNKVDHAVAAVGYG
PNYILIKNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYPVKN
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| BDBM50304797 |
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| n/a |
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| Name | BDBM50304797 |
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| Synonyms: | (S)-benzyl 1-(2-cyano-1-methyl-2-pentylhydrazinyl)-1-oxo-3-phenylpropan-2-ylcarbamate | CHEMBL594719 | acs.jmedchem.1c00409_ST.403 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H30N4O3 |
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| Mol. Mass. | 422.52 |
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| SMILES | CCCCCN(C#N)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1 |r| |
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| Structure | 
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