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Target5-hydroxytryptamine receptor 2A
LigandBDBM50304806
Substrate/Competitorn/a
Meas. Tech.ChEMBL_606260
EC50 1311±n/a nM
Citation Liu KKCornelius PPatterson TAZeng YSantucci STomlinson EGibbons CMaurer TSMarala RBrown JKong JXLee EWerner WWenzel ZVage C Design and synthesis of orally-active and selective azaindane 5HT2c agonist for the treatment of obesity. Bioorg Med Chem Lett 20:266-71 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
5-hydroxytryptamine receptor 2A
Name:Dopamine D2 receptor and serotonin 2a receptor
Synonyms:5-HT-2 | 5-HT-2A | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT-2A) | 5-hydroxytryptamine receptor 2A (5HT-2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | HTR2 | HTR2A | Serotonin receptor 2A
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:52607.65
Organism:Homo sapiens (Human)
Description:n/a
Residue:471
Sequence:
MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGC
LSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIH
REPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGA
LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYK
SSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV
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  Blast E-value cutoff:
BDBM50304806
n/a
NameBDBM50304806
Synonyms:(R)-7-(2-chlorophenoxy)-2-(piperazin-1-yl)-6,7-dihydro-5H-cyclopenta[b]pyridine | CHEMBL595553
TypeSmall organic molecule
Emp. Form.C18H20ClN3O
Mol. Mass.329.824
SMILESClc1ccccc1O[C@@H]1CCc2ccc(nc12)N1CCNCC1 |r|
Structure
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