Ki Summary

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Target

Calmodulin-sensitive adenylate cyclase

Ligand

BDBM50304913

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_606615 (CHEMBL1071251)

100±n/a nM

Citation

Emmrich, T; El-Tayeb, A; Taha, H; Seifert, R; Müller, CE; Link, A Synthesis of a hydrolytically stable, fluorescent-labeled ATP analog as a tool for probing adenylyl cyclases. Bioorg Med Chem Lett20:232-5 (2010) [PubMed] Article

More Info.:

Get all data from this article, Assay Method

Calmodulin-sensitive adenylate cyclase

Name:

Calmodulin-sensitive adenylate cyclase

Synonyms:

CYAA_BACAN | cya

Type:

PROTEIN

Mol. Mass.:

92481.33

Organism:

Bacillus anthracis

Description:

ChEMBL_606615

Residue:

800

Sequence:

MTRNKFIPNKFSIISFSVLLFAISSSQAIEVNAMNEHYTESDIKRNHKTEKNKTEKEKFK
DSINNLVKTEFTNETLDKIQQTQDLLKKIPKDVLEIYSELGGEIYFTDIDLVEHKELQDL
SEEEKNSMNSRGEKVPFASRFVFEKKRETPKLIINIKDYAINSEQSKEVYYEIGKGISLD
IISKDKSLDPEFLNLIKSLSDDSDSSDLLFSQKFKEKLELNNKSIDINFIKENLTEFQHA
FSLAFSYYFAPDHRTVLELYAPDMFEYMNKLEKGGFEKISESLKKEGVEKDRIDVLKGEK
ALKASGLVPEHADAFKKIARELNTYILFRPVNKLATNLIKSGVATKGLNVHGKSSDWGPV
AGYIPFDQDLSKKHGQQLAVEKGNLENKKSITEHEGEIGKIPLKLDHLRIEELKENGIIL
KGKKEIDNGKKYYLLESNNQVYEFRISDENNEVQYKTKEGKITVLGEKFNWRNIEVMAKN
VEGVLKPLTADYDLFALAPSLTEIKKQIPQKEWDKVVNTPNSLEKQKGVTNLLIKYGIER
KPDSTKGTLSNWQKQMLDRLNEAVKYTGYTGGDVVNHGTEQDNEEFPEKDNEIFIINPEG
EFILTKNWEMTGRFIEKNITGKDYLYYFNRSYNKIAPGNKAYIEWTDPITKAKINTIPTS
AEFIKNLSSIRRSSNVGVYKDSGDKDEFAKKESVKKIAGYLSDYYNSANHIFSQEKKRKI
SIFRGIQAYNEIENVLKSKQIAPEYKNYFQYLKERITNQVQLLLTHQKSNIEFKLLYKQL
NFTENETDNFEVFQKIIDEK

BDBM50304913

n/a

Name

BDBM50304913

Synonyms:

(2R,3R,4R,5R)-2-(6-amino-2-oxopyrimidin-1(2H)-yl)-4-hydroxy-5-((hydroxy(hydroxy(phosphonooxy)phosphoryloxy)phosphoryloxy)methyl)tetrahydrofuran-3-yl 2-(methylamino)benzoate | CHEMBL594333

Type

Small organic molecule

Emp. Form.

C17H23N4O15P3

Mol. Mass.

616.3036

SMILES

CNc1ccccc1C(=O)O[C@@H]1[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]1n1ccc(N)nc1=O |r|

Structure