| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
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| Ligand | BDBM50304935 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_606629 (CHEMBL1071856) |
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| EC50 | 20±n/a nM |
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| Citation |  Sellitto, I; Le Bourdonnec, B; Worm, K; Goodman, A; Savolainen, MA; Chu, GH; Ajello, CW; Saeui, CT; Leister, LK; Cassel, JA; Dehaven, RN; Labuda, CJ; Koblish, M; Little, PJ; Brogdon, BL; Smith, SA; Dolle, RE Novel sulfamoyl benzamides as selective CB(2) agonists with improved in vitro metabolic stability. Bioorg Med Chem Lett20:387-91 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 2 |
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| Name: | Cannabinoid receptor 2 |
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| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CNR2_RAT | Cannabinoid CB2 receptor | Cannabinoid receptor | Cnr2 | rCB2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 39366.68 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | Q9QZN9 |
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| Residue: | 360 |
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| Sequence: | MAGCRELELTNGSNGGLEFNPMKEYMILSDAQQIAVAVLCTLMGLLSALENVAVLYLILS
SQRLRRKPSYLFIGSLAGADFLASVIFACNFVIFHVFHGVDSRNIFLLKIGSVTMTFTAS
VGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALGVMWVLSALISYLPLMGWTCCPSPCS
ELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHQHVASLAEHQDRQVPGIARMRLD
VRLAKTLGLVMAVLLICWFPALALMGHSLVTTLSDKVKEAFAFCSMLCLVNSMINPIIYA
LRSGEIRSAAQHCLTGWKKYLQGLGSEGKEEAPKSSVTETEAEVKTTTGPGSRTPGCSNC
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| BDBM50304935 |
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| n/a |
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| Name | BDBM50304935 |
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| Synonyms: | CHEMBL605199 | N-[3-(1,1-Dioxo-1lambda*6*-thiomorpholine-4-sulfonyl)-4,5-dimethyl-phenyl]-2,2-dimethyl-butyramide |
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| Type | Small organic molecule |
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| Emp. Form. | C18H28N2O5S2 |
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| Mol. Mass. | 416.555 |
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| SMILES | CCC(C)(C)C(=O)Nc1cc(C)c(C)c(c1)S(=O)(=O)N1CCS(=O)(=O)CC1 |
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| Structure | 
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