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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Mu-type opioid receptor | ||
| Ligand | BDBM50305085 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_603077 (CHEMBL1048560) | ||
| Ki | >10000±n/a nM | ||
| Citation |  Li, W; Tao, YM; Tang, Y; Xu, XJ; Chen, J; Fu, W; Wang, XH; Chao, B; Sheng, W; Xie, Q; Qiu, ZB; Liu, JG Highly selective and potent mu opioid ligands by unexpected substituent on morphine skeleton. Bioorg Med Chem Lett20:418-21 (2010) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Mu-type opioid receptor | |||
| Name: | Mu-type opioid receptor | ||
| Synonyms: | MOR-1 | MUOR1 | Mu-type opioid receptor (MOR) | OPIATE Mu | OPRM_RAT | Opiate non-selective | Opioid receptor B | Oprm1 | Ror-b | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 44503.11 | ||
| Organism: | Rattus norvegicus (rat) | ||
| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the mu opioid receptor. | ||
| Residue: | 398 | ||
| Sequence: |
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| BDBM50305085 | |||
| n/a | |||
| Name | BDBM50305085 | ||
| Synonyms: | 8alpha-phenyl-6alpha,14alpha-endo-Ethenotetrahydrothebaine | CHEMBL594124 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C27H29NO3 | ||
| Mol. Mass. | 415.5241 | ||
| SMILES | COc1ccc2C[C@H]3N(C)CC[C@@]45[C@@H](Oc1c24)[C@]1(C[C@@H](c2ccccc2)[C@]35C=C1)OC |r,wU:7.7,17.35,wD:13.13,12.18,26.32,19.22,c:33,(-7.92,.41,;-6.59,1.18,;-5.24,.4,;-3.92,1.17,;-2.58,.41,;-2.58,-1.14,;-1.24,-1.9,;-1.24,-3.45,;.09,-4.22,;1.24,-5.25,;-1.05,-2.67,;-2.59,-2.67,;-3.91,-3.45,;-5.25,-4.22,;-6.03,-2.47,;-5.25,-1.14,;-3.91,-1.91,;-5.25,-5.76,;-3.91,-6.53,;-2.58,-5.76,;-1.25,-6.53,;-1.25,-8.07,;.08,-8.84,;1.42,-8.07,;1.41,-6.53,;.08,-5.76,;-2.58,-4.23,;-3.89,-4.21,;-3.89,-5.84,;-6.73,-6.21,;-7.07,-7.71,)| | ||
| Structure | 
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