| Reaction Details |
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 | Report a problem with these data |
| Target | Carboxypeptidase B |
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| Ligand | BDBM50305348 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_603569 (CHEMBL1069124) |
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| Ki | 27±n/a nM |
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| Citation |  Owen, DR; Bull, DJ; Bunnage, ME; Glossop, MS; Maguire, RJ; Strang, RS Oxygenated analogues of UK-396082 as inhibitors of activated thrombin activatable fibrinolysis inhibitor. Bioorg Med Chem Lett20:92-6 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carboxypeptidase B |
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| Name: | Carboxypeptidase B |
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| Synonyms: | CBPB1_HUMAN | CPB | CPB1 | Carboxypeptidase B | PASP | PCPB | Pancreas-specific protein | Thrombin-activatable fibrinolysis (TAFI) |
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| Type: | Enzyme |
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| Mol. Mass.: | 47367.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P15086 |
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| Residue: | 417 |
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| Sequence: | MLALLVLVTVALASAHHGGEHFEGEKVFRVNVEDENHINIIRELASTTQIDFWKPDSVTQ
IKPHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFDSRVRATGHSYEKYN
KWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAIFMDCGFHAREW
ISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWRKTRSTH
TGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSSIKAY
LTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTIYPAAG
GSDDWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAIKYVASYVLEHLY
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| BDBM50305348 |
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| n/a |
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| Name | BDBM50305348 |
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| Synonyms: | (S)-2-(2-aminoethoxy)-3-(1-(2-cyclohexylethyl)-1H-imidazol-4-yl)propanoic acid | CHEMBL594359 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H27N3O3 |
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| Mol. Mass. | 309.4039 |
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| SMILES | NCCO[C@@H](Cc1cn(CCC2CCCCC2)cn1)C(O)=O |r| |
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| Structure | 
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