| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Oxytocin receptor |
|---|
| Ligand | BDBM50305521 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_604218 (CHEMBL1050363) |
|---|
| Ki | 55.1±n/a nM |
|---|
| Citation |  Brown, A; Brown, TB; Calabrese, A; Ellis, D; Puhalo, N; Ralph, M; Watson, L Triazole oxytocin antagonists: Identification of an aryloxyazetidine replacement for a biaryl substituent. Bioorg Med Chem Lett20:516-20 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Oxytocin receptor |
|---|
| Name: | Oxytocin receptor |
|---|
| Synonyms: | OT-R | OXTR | OXYR_HUMAN | Oxytocin |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 42793.26 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Oxytocin OXTR HEK293::B2R9L7 |
|---|
| Residue: | 389 |
|---|
| Sequence: | MEGALAANWSAEAANASAAPPGAEGNRTAGPPRRNEALARVEVAVLCLILLLALSGNACV
LLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQV
VGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLATWLGCLVASAPQVHIFSLREV
ADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAA
AEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVW
DANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGRRLGET
SASKKSNSSSFVLSHRSSSQRSCSQPSTA
|
|
|
|---|
| BDBM50305521 |
|---|
| n/a |
|---|
| Name | BDBM50305521 |
|---|
| Synonyms: | 5-(3-(3-(2-chlorophenoxy)azetidin-1-yl)-5-methyl-4H-1,2,4-triazol-4-yl)-2-methoxypyridine | CHEMBL590099 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H18ClN5O2 |
|---|
| Mol. Mass. | 371.821 |
|---|
| SMILES | COc1ccc(cn1)-n1c(C)nnc1N1CC(C1)Oc1ccccc1Cl |
|---|
| Structure | 
|
|---|
Search and Browse
