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TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1
LigandBDBM50305680
Substrate/Competitorn/a
Meas. Tech.ChEMBL_604567 (CHEMBL1065476)
IC50 260±n/a nM
Citation Potter, AJRay, SGueritz, LNunns, CLBryant, CJScrace, SFMatassova, NBaker, LDokurno, PRobinson, DASurgenor, AEDavis, BMurray, JBRichardson, CMMoore, JD Structure-guided design of alpha-amino acid-derived Pin1 inhibitors. Bioorg Med Chem Lett20:586-90 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Name:Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Synonyms:PIN1 | PIN1_HUMAN | PPIase Pin1 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Type:PROTEIN
Mol. Mass.:18248.11
Organism:Homo sapiens (Human)
Description:ChEMBL_1502595
Residue:163
Sequence:
MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHL
LVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARG
DLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE
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BDBM50305680
n/a
NameBDBM50305680
Synonyms:(R)-methyl 3-(1H-benzo[d]imidazol-2-yl)-2-(1-methyl-3-phenyl-1H-pyrazole-5-carboxamido)propanoate | CHEMBL594125
TypeSmall organic molecule
Emp. Form.C22H21N5O3
Mol. Mass.403.4338
SMILESCOC(=O)[C@@H](Cc1nc2ccccc2[nH]1)NC(=O)c1cc(nn1C)-c1ccccc1 |r|
Structure
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