| Reaction Details |
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 | Report a problem with these data |
| Target | Free fatty acid receptor 2 |
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| Ligand | BDBM50305906 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_605612 (CHEMBL1069216) |
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| IC50 | 700±n/a nM |
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| Citation |  Wang, Y; Jiao, X; Kayser, F; Liu, J; Wang, Z; Wanska, M; Greenberg, J; Weiszmann, J; Ge, H; Tian, H; Wong, S; Schwandner, R; Lee, T; Li, Y The first synthetic agonists of FFA2: Discovery and SAR of phenylacetamides as allosteric modulators. Bioorg Med Chem Lett20:493-8 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Free fatty acid receptor 2 |
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| Name: | Free fatty acid receptor 2 |
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| Synonyms: | FFA2 | FFAR2 | FFAR2_HUMAN | G-protein coupled receptor 43 | GPCR43 | GPR43 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 37156.44 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1508993 |
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| Residue: | 330 |
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| Sequence: | MLPDWKSSLILMAYIIIFLTGLPANLLALRAFVGRIRQPQPAPVHILLLSLTLADLLLLL
LLPFKIIEAASNFRWYLPKVVCALTSFGFYSSIYCSTWLLAGISIERYLGVAFPVQYKLS
RRPLYGVIAALVAWVMSFGHCTIVIIVQYLNTTEQVRSGNEITCYENFTDNQLDVVLPVR
LELCLVLFFIPMAVTIFCYWRFVWIMLSQPLVGAQRRRRAVGLAVVTLLNFLVCFGPYNV
SHLVGYHQRKSPWWRSIAVVFSSLNASLDPLLFYFSSSVVRRAFGRGLQVLRNQGSSLLG
RRGKDTAEGTNEDRGVGQGEGMPSSDFTTE
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| BDBM50305906 |
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| n/a |
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| Name | BDBM50305906 |
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| Synonyms: | (S)-N-(5-bromothiazol-2-yl)-2-(4-chlorophenyl)-3,3-dimethylbutanamide | CHEMBL593344 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H16BrClN2OS |
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| Mol. Mass. | 387.722 |
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| SMILES | CC(C)(C)[C@H](C(=O)Nc1ncc(Br)s1)c1ccc(Cl)cc1 |r| |
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| Structure | 
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