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TargetCannabinoid receptor 2
LigandBDBM50306000
Substrate/Competitorn/a
Meas. Tech.ChEMBL_605682
Ki 1.1±n/a nM
Citation Gilbert EJZhou GWong MKTong LShankar BBHuang CKelly JLavey BJMcCombie SWChen LRizvi RDong YShu YKozlowski JAShih NYHipkin RWGonsiorek WMalikzay ALunn CAFavreau LLundell DJ Non-aromatic A-ring replacement in the triaryl bis-sulfone CB2 receptor inhibitors. Bioorg Med Chem Lett 20:608-11 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Cannabinoid receptor 2
Name:Cannabinoid receptor 2
Synonyms:CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:39690.94
Organism:Homo sapiens (Human)
Description:P34972
Residue:360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS
SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS
VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS
ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD
VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA
LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
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  Blast E-value cutoff:
BDBM50306000
n/a
NameBDBM50306000
Synonyms:CHEMBL596133 | N-(6-(5-chloro-2-(2-fluorophenylsulfonyl)phenylsulfonyl)-6-azaspiro[2.5]octan-1-yl)methanesulfonamide
TypeSmall organic molecule
Emp. Form.C20H22ClFN2O6S3
Mol. Mass.537.045
SMILESCS(=O)(=O)NC1CC11CCN(CC1)S(=O)(=O)c1cc(Cl)ccc1S(=O)(=O)c1ccccc1F
Structure
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