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TargetDelta-type opioid receptor
LigandBDBM50306301
Substrate/Competitorn/a
Meas. Tech.ChEMBL_607037 (CHEMBL1074665)
Ki 2.3±n/a nM
Citation Liras, SMcHardy, SFAllen, MPSegelstein, BEHeck, SDBryce, DKSchmidt, AWVanase-Frawley, MCallegari, EMcLean, S Biaryl piperidines as potent and selective delta opioid receptor ligands. Bioorg Med Chem Lett20:503-7 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Delta-type opioid receptor
Name:Delta-type opioid receptor
Synonyms:D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:40382.98
Organism:Homo sapiens (Human)
Description:Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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BDBM50306301
n/a
NameBDBM50306301
Synonyms:3-(1-(cyclopropylmethyl)-4-(4-(3-hydroxypentan-3-yl)phenyl)piperidin-4-yl)benzamide | CHEMBL593583
TypeSmall organic molecule
Emp. Form.C27H36N2O2
Mol. Mass.420.5869
SMILESCCC(O)(CC)c1ccc(cc1)C1(CCN(CC2CC2)CC1)c1cccc(c1)C(N)=O
Structure
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