| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Delta-type opioid receptor |
|---|
| Ligand | BDBM50306300 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_607037 (CHEMBL1074665) |
|---|
| Ki | 11±n/a nM |
|---|
| Citation |  Liras, S; McHardy, SF; Allen, MP; Segelstein, BE; Heck, SD; Bryce, DK; Schmidt, AW; Vanase-Frawley, M; Callegari, E; McLean, S Biaryl piperidines as potent and selective delta opioid receptor ligands. Bioorg Med Chem Lett20:503-7 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Delta-type opioid receptor |
|---|
| Name: | Delta-type opioid receptor |
|---|
| Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 40382.98 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
|---|
| Residue: | 372 |
|---|
| Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
|
|
|
|---|
| BDBM50306300 |
|---|
| n/a |
|---|
| Name | BDBM50306300 |
|---|
| Synonyms: | 4-(4-(3-hydroxyphenyl)-1-(2-methylpentyl)piperidin-4-yl)-N,N-dimethylbenzamide | CHEMBL603428 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H36N2O2 |
|---|
| Mol. Mass. | 408.5762 |
|---|
| SMILES | CCCC(C)CN1CCC(CC1)(c1ccc(cc1)C(=O)N(C)C)c1cccc(O)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
