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TargetAdenosine receptor A2a
LigandBDBM50306775
Substrate/Competitorn/a
Meas. Tech.ChEMBL_611932 (CHEMBL1071493)
Ki 120000±n/a nM
Citation Katritch, VJaakola, VPLane, JRLin, JIjzerman, APYeager, MKufareva, IStevens, RCAbagyan, R Structure-based discovery of novel chemotypes for adenosine A(2A) receptor antagonists. J Med Chem53:1799-809 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Adenosine receptor A2a
Name:Adenosine receptor A2a
Synonyms:A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:44716.46
Organism:Homo sapiens (Human)
Description:P29274
Residue:412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50306775
n/a
NameBDBM50306775
Synonyms:1,4-diamino-N-butyl-9,10-dioxo-9,10-dihydroanthracene-2-carboxamide | CHEMBL601628
TypeSmall organic molecule
Emp. Form.C19H19N3O3
Mol. Mass.337.3725
SMILESCCCCNC(=O)c1cc(N)c2C(=O)c3ccccc3C(=O)c2c1N
Structure
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