| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 1 |
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| Ligand | BDBM50310065 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_612189 (CHEMBL1074127) |
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| IC50 | 189±n/a nM |
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| Citation |  Seo, HJ; Kim, MJ; Lee, SH; Lee, SH; Jung, ME; Kim, MS; Ahn, K; Kim, J; Lee, J Synthesis and structure-activity relationship of 1,2,4-triazole-containing diarylpyrazolyl carboxamide as CB1 cannabinoid receptor-ligand. Bioorg Med Chem18:1149-62 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 1 |
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| Name: | Cannabinoid receptor 1 |
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| Synonyms: | Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_RAT | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cnr1 | Skr6 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 52856.55 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P20272 |
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| Residue: | 473 |
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| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEENIQCGENFMDMECFMILNPSQQLAI
AVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHV
FHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCL
MWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILW
KAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPL
LAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTA
QPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
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| BDBM50310065 |
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| n/a |
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| Name | BDBM50310065 |
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| Synonyms: | 4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-chlorophenyl)-N'-(cyclohexanecarbonyl)-1-(2,4-dichlorophenyl)-1H-pyrazole-3-carbohydrazide | CHEMBL609562 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H24Cl3N7O2 |
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| Mol. Mass. | 572.873 |
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| SMILES | Clc1ccc(cc1)-c1c(Cn2cncn2)c(nn1-c1ccc(Cl)cc1Cl)C(=O)NNC(=O)C1CCCCC1 |
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| Structure | 
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