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TargetSigma non-opioid intracellular receptor 1
LigandBDBM50310078
Substrate/Competitorn/a
Meas. Tech.ChEMBL_612206 (CHEMBL1074144)
Ki 1.29±n/a nM
Citation Rossi, DUrbano, MPedrali, ASerra, MZampieri, DMamolo, MGLaggner, CZanette, CFlorio, CSchepmann, DWuensch, BAzzolina, OCollina, S Design, synthesis and SAR analysis of novel selective sigma1 ligands (Part 2). Bioorg Med Chem18:1204-12 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Sigma non-opioid intracellular receptor 1
Name:Sigma non-opioid intracellular receptor 1
Synonyms:Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1
Type:Enzyme Catalytic Domain
Mol. Mass.:25266.54
Organism:RAT
Description:Q9R0C9
Residue:223
Sequence:
MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRY
WAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
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  Blast E-value cutoff:
BDBM50310078
n/a
NameBDBM50310078
Synonyms:(R/S)-1-(3-(6-Methoxynaphthalen-2-yl)butyl)piperidine | CHEMBL597643
TypeSmall organic molecule
Emp. Form.C20H27NO
Mol. Mass.297.4345
SMILESCOc1ccc2cc(ccc2c1)C(C)CCN1CCCCC1
Structure
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