| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-2C adrenergic receptor |
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| Ligand | BDBM50311076 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_619545 (CHEMBL1111402) |
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| Ki | >10000±n/a nM |
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| Citation |  Donohue, SR; Varnäs, K; Jia, Z; Gulyás, B; Pike, VW; Halldin, C Synthesis and in vitro autoradiographic evaluation of a novel high-affinity radioiodinated ligand for imaging brain cannabinoid subtype-1 receptors. Bioorg Med Chem Lett19:6209-12 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-2C adrenergic receptor |
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| Name: | Alpha-2C adrenergic receptor |
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| Synonyms: | ADA2C_HUMAN | ADRA2C | ADRA2L2 | ADRA2RL2 | Adrenergic alpha2C | Adrenergic receptor | Adrenergic receptor alpha | Adrenergic, alpha-2C-, receptor | Alpha-2 adrenergic receptor subtype C4 | Alpha-2C adrenoceptor | Alpha-2C adrenoreceptor | adrenergic, alpha-2C-, receptor [Homo sapiens] |
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| Type: | Enzyme |
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| Mol. Mass.: | 49552.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P18825 |
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| Residue: | 462 |
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| Sequence: | MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGF
LIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFG
QVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISA
VISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLR
TRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGA
LRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRR
RRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFK
FFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ
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| BDBM50311076 |
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| n/a |
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| Name | BDBM50311076 |
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| Synonyms: | CHEMBL1079079 | [125I]1-(2-iodophenyl)-4-cyano-5-(4-methoxyphenyl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxylate |
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| Type | Small organic molecule |
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| Emp. Form. | C23H22IN5O2 |
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| Mol. Mass. | 527.3576 |
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| SMILES | COc1ccc(cc1)-c1c(C#N)c(nn1-c1ccccc1I)C(=O)NN1CCCCC1 |
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| Structure | 
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