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TargetNociceptin receptor
LigandBDBM50311485
Substrate/Competitorn/a
Meas. Tech.ChEMBL_622957 (CHEMBL1112209)
Ki 2.5±n/a nM
Citation Palin, RClark, JKEvans, LFeilden, HFletcher, DHamilton, NMHoughton, AKJones, PSMcArthur, DMontgomery, BRatcliffe, PDSmith, ARSutherland, AWeston, MAWishart, G Rapid access towards follow-up NOP receptor agonists using a knowledge based approach. Bioorg Med Chem Lett19:6441-6 (2009) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Nociceptin receptor
Name:Nociceptin receptor
Synonyms:KOR-3 | Kappa-type 3 opioid receptor | Mu-type opioid receptor (Mu) | NOP | Nociceptin Receptor (ORL1 Receptor) | Nociceptin receptor (NOP) | Nociceptin receptor (ORL-1) | Nociceptin receptor (ORL1) | Nociceptin/Orphanin FQ, NOP receptor | OOR | OPIATE ORL-1 | OPRL1 | OPRL1 protein | OPRX_HUMAN | ORL1 | ORL1 receptor | Opioid receptor like-1 | Orphanin FQ receptor | Orphanin FQ receptor (ORL1) | P41146
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:40702.87
Organism:Homo sapiens (Human)
Description:P41146
Residue:370
Sequence:
MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLA
VCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGN
ALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASV
VGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIR
RLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAI
LRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRDVQVSDRVRSIAKDVALAC
KTSETVPRPA
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  Blast E-value cutoff:
BDBM50311485
n/a
NameBDBM50311485
Synonyms:2-[3-(1-Cyclodecyl-piperidin-4-yl)-2,2-dioxo-2,3-dihydro-2lambda*6*-benzo[1,2,5]thiadiazol-1-yl]-N-methyl-acetamide | CHEMBL1079571
TypeSmall organic molecule
Emp. Form.C24H38N4O3S
Mol. Mass.462.649
SMILESCNC(=O)CN1c2ccccc2N(C2CCN(CC2)C2CCCCCCCCC2)S1(=O)=O
Structure
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