Reaction Details | |||
---|---|---|---|
Report a problem with these data | |||
Target | Mu-type opioid receptor | ||
Ligand | BDBM50311481 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_622958 (CHEMBL1112210) | ||
Ki | 7.3±n/a nM | ||
Citation | Palin, R; Clark, JK; Evans, L; Feilden, H; Fletcher, D; Hamilton, NM; Houghton, AK; Jones, PS; McArthur, D; Montgomery, B; Ratcliffe, PD; Smith, AR; Sutherland, A; Weston, MA; Wishart, G Rapid access towards follow-up NOP receptor agonists using a knowledge based approach. Bioorg Med Chem Lett19:6441-6 (2009) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Mu-type opioid receptor | |||
Name: | Mu-type opioid receptor | ||
Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 | ||
Type: | G Protein-Coupled Receptor (GPCR) | ||
Mol. Mass.: | 44789.51 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P35372 | ||
Residue: | 400 | ||
Sequence: |
| ||
BDBM50311481 | |||
n/a | |||
Name | BDBM50311481 | ||
Synonyms: | 2-(8-(4-tert-butylcyclohexyl)-1-oxo-4-phenyl-2,3,8-triazaspiro[4.5]dec-3-en-2-yl)-N-methylacetamide | CHEMBL1079940 | ||
Type | Small organic molecule | ||
Emp. Form. | C26H38N4O2 | ||
Mol. Mass. | 438.6055 | ||
SMILES | CNC(=O)CN1N=C(c2ccccc2)C2(CCN(CC2)C2CCC(CC2)C(C)(C)C)C1=O |t:6,(25.94,-40.59,;24.4,-40.58,;23.63,-41.91,;24.4,-43.25,;22.09,-41.91,;21.32,-43.24,;21.8,-44.7,;20.55,-45.61,;20.56,-47.15,;19.24,-47.92,;19.23,-49.46,;20.57,-50.23,;21.9,-49.46,;21.9,-47.91,;19.3,-44.7,;18.52,-43.37,;16.98,-43.37,;16.21,-44.71,;16.99,-46.05,;18.54,-46.05,;14.67,-44.7,;13.9,-43.37,;12.37,-43.37,;11.6,-44.7,;12.37,-46.03,;13.91,-46.04,;10.06,-44.7,;9.29,-43.36,;9.28,-46.03,;10.46,-43.21,;19.78,-43.24,;18.87,-42,)| | ||
Structure |