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TargetCannabinoid receptor 1/Mu-type opioid receptor
LigandBDBM50311491
Substrate/Competitorn/a
Meas. Tech.ChEMBL_622958
Ki 3.7±n/a nM
Citation Palin RClark JKEvans LFeilden HFletcher DHamilton NMHoughton AKJones PSMcArthur DMontgomery BRatcliffe PDSmith ARSutherland AWeston MAWishart G Rapid access towards follow-up NOP receptor agonists using a knowledge based approach. Bioorg Med Chem Lett 19:6441-6 (2009) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Cannabinoid receptor 1/Mu-type opioid receptor
Name:Cannabinoid receptor 1/Mu-type opioid receptor
Synonyms:M-OR-1 | MOP | MOR-1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | hMOP | mu-type opioid receptor isoform MOR-1
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:44789.51
Organism:Homo sapiens (Human)
Description:P35372
Residue:400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
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  Blast E-value cutoff:
BDBM50311491
n/a
NameBDBM50311491
Synonyms:2-(3-(1-(biphenyl-2-ylmethyl)piperidin-4-yl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N-methylacetamide | CHEMBL1079562
TypeSmall organic molecule
Emp. Form.C28H30N4O2
Mol. Mass.454.5634
SMILESCNC(=O)Cn1c2ccccc2n(C2CCN(Cc3ccccc3-c3ccccc3)CC2)c1=O
Structure
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