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TargetLow molecular weight protein-tyrosine phosphatase A
LigandBDBM50312255
Substrate/Competitorn/a
Meas. Tech.ChEMBL_621991 (CHEMBL1106782)
Ki 16800±n/a nM
Citation Rawls, KALang, PTTakeuchi, JImamura, SBaguley, TDGrundner, CAlber, TEllman, JA Fragment-based discovery of selective inhibitors of the Mycobacterium tuberculosis protein tyrosine phosphatase PtpA. Bioorg Med Chem Lett19:6851-4 (2009) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Low molecular weight protein-tyrosine phosphatase A
Name:Low molecular weight protein-tyrosine phosphatase A
Synonyms:PTPA_MYCTU | PTPase | Probable low molecular weight protein-tyrosine-phosphatase | Protein Tyrosine Phosphatase PTPA | mptpA | ptpA
Type:Hydrolase
Mol. Mass.:17891.84
Organism:Mycobacterium tuberculosis
Description:n/a
Residue:163
Sequence:
MSDPLHVTFVCTGNICRSPMAEKMFAQQLRHRGLGDAVRVTSAGTGNWHVGSCADERAAG
VLRAHGYPTDHRAAQVGTEHLAADLLVALDRNHARLLRQLGVEAARVRMLRSFDPRSGTH
ALDVEDPYYGDHSDFEEVFAVIESALPGLHDWVDERLARNGPS
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BDBM50312255
n/a
NameBDBM50312255
Synonyms:(4-(4-chlorophenylcarbamoyl)phenyl)difluoromethylphosphonic acid | CHEMBL1080495
TypeSmall organic molecule
Emp. Form.C14H11ClF2NO4P
Mol. Mass.361.665
SMILESOP(O)(=O)C(F)(F)c1ccc(cc1)C(=O)Nc1ccc(Cl)cc1
Structure
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