| Reaction Details |
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 | Report a problem with these data |
| Target | Sialidase-2 |
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| Ligand | BDBM23411 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_617801 (CHEMBL1100507) |
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| IC50 | 55000±n/a nM |
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| Citation |  Arioka, S; Sakagami, M; Uematsu, R; Yamaguchi, H; Togame, H; Takemoto, H; Hinou, H; Nishimura, S Potent inhibitor scaffold against Trypanosoma cruzi trans-sialidase. Bioorg Med Chem18:1633-40 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sialidase-2 |
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| Name: | Sialidase-2 |
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| Synonyms: | Cytosolic sialidase | N-acetyl-alpha-neuraminidase 2 | NEU2 | NEUR2_HUMAN | Sialidase 2 | Sialidase-2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42256.20 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_960638 |
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| Residue: | 380 |
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| Sequence: | MASLPVLQKESVFQSGAHAYRIPALLYLPGQQSLLAFAEQRASKKDEHAELIVLRRGDYD
APTHQVQWQAQEVVAQARLDGHRSMNPCPLYDAQTGTLFLFFIAIPGQVTEQQQLQTRAN
VTRLCQVTSTDHGRTWSSPRDLTDAAIGPAYREWSTFAVGPGHCLQLHDRARSLVVPAYA
YRKLHPIQRPIPSAFCFLSHDHGRTWARGHFVAQDTLECQVAEVETGEQRVVTLNARSHL
RARVQAQSTNDGLDFQESQLVKKLVEPPPQGCQGSVISFPSPRSGPGSPAQWLLYTHPTH
SWQRADLGAYLNPRPPAPEAWSEPVLLAKGSCAYSDLQSMGTGPDGSPLFGCLYEANDYE
EIVFLMFTLKQAFPAEYLPQ
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| BDBM23411 |
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| n/a |
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| Name | BDBM23411 |
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| Synonyms: | 5,6,7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one | Scutel-larei | Scutellarein | Scutellarein (2) | Scutellarein (28) | US10252984, Table 2.2 |
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| Type | flavone |
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| Emp. Form. | C15H10O6 |
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| Mol. Mass. | 286.2363 |
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| SMILES | Oc1ccc(cc1)-c1cc(=O)c2c(O)c(O)c(O)cc2o1 |
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| Structure | 
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