| Reaction Details |
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 | Report a problem with these data |
| Target | Sphingosine 1-phosphate receptor 2 |
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| Ligand | BDBM50313497 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_617666 (CHEMBL1101462) |
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| IC50 | >22000±n/a nM |
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| Citation |  Högenauer, K; Hinterding, K; Nussbaumer, P S1P receptor mediated activity of FTY720 phosphate mimics. Bioorg Med Chem Lett20:1485-7 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sphingosine 1-phosphate receptor 2 |
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| Name: | Sphingosine 1-phosphate receptor 2 |
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| Synonyms: | EDG5 | S1P2 | S1PR2 | S1PR2_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-5 | Sphingosine-1-phosphate receptor 2 | ndothelial differentiation G-protein coupled receptor 5 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 38883.16 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Membranes isolated from S1P2-transfected CHO cells were used in ligand binding assay. |
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| Residue: | 353 |
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| Sequence: | MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVAR
NSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASV
FSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACS
TVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLG
VFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVL
RPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
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| BDBM50313497 |
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| n/a |
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| Name | BDBM50313497 |
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| Synonyms: | (S)-1-(4-(heptyloxy)phenyl)-3-methyl-5-(1H-tetrazol-5-yl)pentan-3-amine | CHEMBL1085191 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H33N5O |
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| Mol. Mass. | 359.5089 |
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| SMILES | CCCCCCCOc1ccc(CC[C@](C)(N)CCc2nnn[nH]2)cc1 |r| |
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| Structure | 
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