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TargetSphingosine 1-phosphate receptor 5
LigandBDBM50313499
Substrate/Competitorn/a
Meas. Tech.ChEMBL_617669 (CHEMBL1101465)
EC50 2.2±n/a nM
Citation Högenauer, K; Hinterding, K; Nussbaumer, P S1P receptor mediated activity of FTY720 phosphate mimics. Bioorg Med Chem Lett20:1485-7 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Sphingosine 1-phosphate receptor 5
Name:Sphingosine 1-phosphate receptor 5
Synonyms:EDG8 | Endothelial differentiation sphingolipid G-protein-coupled receptor 8 | S1P5 | S1PR5 | S1PR5_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-8
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:41796.42
Organism:Homo sapiens (Human)
Description:n/a
Residue:398
Sequence:
MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAVVCLAVCAFIVLENLAVLLV
LGRHPRFHAPMFLLLGSLTLSDLLAGAAYAANILLSGPLTLKLSPALWFAREGGVFVALT
ASVLSLLAIALERSLTMARRGPAPVSSRGRTLAMAAAAWGVSLLLGLLPALGWNCLGRLD
ACSTVLPLYAKAYVLFCVLAFVGILAAICALYARIYCQVRANARRLPARPGTAGTTSTRA
RRKPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARTCPVLLQADPFLGLAMANSL
LNPIIYTLTNRDLRHALLRLVCCGRHSCGRDPSGSQQSASAAEASGGLRRCLPPGLDGSF
SGSERSSPQRDGLDTSGSTGSPGAPTAARTLVSEPAAD
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BDBM50313499
n/a
NameBDBM50313499
Synonyms:(S)-2-amino-4-(4-(heptyloxy)phenyl)-2-methylbutyl dihydrogen phosphate | CHEMBL1084929
TypeSmall organic molecule
Emp. Form.C18H32NO5P
Mol. Mass.373.4241
SMILESCCCCCCCOc1ccc(CC[C@](C)(N)COP(O)(O)=O)cc1 |r|
Structure
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