| Reaction Details |
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 | Report a problem with these data |
| Target | Oxytocin receptor |
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| Ligand | BDBM50305523 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_615224 (CHEMBL1115874) |
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| Ki | 28.4±n/a nM |
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| Citation |  Brown, A; Ellis, D; Wallace, O; Ralph, M Identification of a urea bioisostere of a triazole oxytocin antagonist. Bioorg Med Chem Lett20:1851-3 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Oxytocin receptor |
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| Name: | Oxytocin receptor |
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| Synonyms: | OT-R | OXTR | OXYR_HUMAN | Oxytocin |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 42793.26 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Oxytocin OXTR HEK293::B2R9L7 |
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| Residue: | 389 |
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| Sequence: | MEGALAANWSAEAANASAAPPGAEGNRTAGPPRRNEALARVEVAVLCLILLLALSGNACV
LLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQV
VGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLATWLGCLVASAPQVHIFSLREV
ADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAA
AEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVW
DANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGRRLGET
SASKKSNSSSFVLSHRSSSQRSCSQPSTA
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| BDBM50305523 |
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| n/a |
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| Name | BDBM50305523 |
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| Synonyms: | 5-(3-(3-(2-chloro-4-fluorophenoxy)azetidin-1-yl)-5-methyl-4H-1,2,4-triazol-4-yl)-2-methoxypyridine | CHEMBL589125 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H17ClFN5O2 |
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| Mol. Mass. | 389.811 |
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| SMILES | COc1ccc(cn1)-n1c(C)nnc1N1CC(C1)Oc1ccc(F)cc1Cl |
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| Structure | 
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