| Reaction Details |
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 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
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| Ligand | BDBM50313913 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_615494 (CHEMBL1105124) |
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| Ki | 2101±n/a nM |
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| Citation |  Robaa, D; Enzensperger, C; Abul Azm, Sel D; El Khawass, el S; El Sayed, O; Lehmann, J Dopamine receptor ligands. Part 18: (1) modification of the structural skeleton of indolobenzazecine-type dopamine receptor antagonists. J Med Chem53:2646-50 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(1A) dopamine receptor |
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| Name: | D(1A) dopamine receptor |
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| Synonyms: | DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A |
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| Type: | Enzyme |
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| Mol. Mass.: | 49303.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21728 |
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| Residue: | 446 |
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| Sequence: | MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTN
FFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVD
RYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLA
ETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKN
CQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGS
GETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIET
VSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPAL
SVILDYDTDVSLEKIQPITQNGQHPT
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| BDBM50313913 |
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| n/a |
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| Name | BDBM50313913 |
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| Synonyms: | 5,6,8,9,10,14c-Hexahydroindolo[3',2':3,4,]pyrido[2,1-a]isoquinoline | CHEMBL1086789 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H18N2 |
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| Mol. Mass. | 274.3596 |
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| SMILES | C1Cc2[nH]c3ccccc3c2C2N1CCc1ccccc21 |
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| Structure | 
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