| Reaction Details |
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 | Report a problem with these data |
| Target | Mitogen-activated protein kinase 9 |
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| Ligand | BDBM50158551 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_624062 (CHEMBL1116948) |
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| IC50 | 650±n/a nM |
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| Citation |  Siddiqui, MA; Reddy, PA Small molecule JNK (c-Jun N-terminal kinase) inhibitors. J Med Chem53:3005-12 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mitogen-activated protein kinase 9 |
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| Name: | Mitogen-activated protein kinase 9 |
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| Synonyms: | JNK-55 | JNK2 | JNK2/JNK3 | MAPK9 | MK09_HUMAN | Mitogen-Activated Protein Kinase 9 (JNK2) | Mitogen-activated protein kinase 8/9 | PRKM9 | SAPK1A | Stress-activated protein kinase JNK2 | c-Jun N-terminal kinase 2 | c-Jun N-terminal kinase 2 (JNK2) |
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| Type: | Enzyme |
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| Mol. Mass.: | 48131.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | JNK-2 was purchased from Upstate Cell Signaling Solutions (formerly Upstate Biotechnology). |
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| Residue: | 424 |
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| Sequence: | MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRP
FQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIH
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQ
LGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESERDKIKTSQARDLLSK
MLVIDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEV
MDWEERSKNGVVKDQPSDAAVSSNATPSQSSSINDISSMSTEQTLASDTDSSLDASTGPL
EGCR
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| BDBM50158551 |
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| n/a |
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| Name | BDBM50158551 |
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| Synonyms: | CHEMBL383955 | N-((5-(4-(1H-benzo[d][1,2,3]triazol-1-yl)piperidin-1-ylsulfonyl)thiophen-2-yl)methyl)-4-chlorobenzamide | N-5-4-1H-benzo[d][1,2,3]triazol-1-yl)piperidin-1-ylsulfonyl)thiophen-2-yl)methyl)-4-chlorobenzamide |
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| Type | Small organic molecule |
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| Emp. Form. | C23H22ClN5O3S2 |
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| Mol. Mass. | 516.035 |
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| SMILES | Clc1ccc(cc1)C(=O)NCc1ccc(s1)S(=O)(=O)N1CCC(CC1)n1nnc2ccccc12 |
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| Structure | 
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