| Reaction Details |
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 | Report a problem with these data |
| Target | Death-associated protein kinase 3 |
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| Ligand | BDBM50314664 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_625624 (CHEMBL1112575) |
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| IC50 | 227.1±n/a nM |
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| Citation |  Okamoto, M; Takayama, K; Shimizu, T; Muroya, A; Furuya, T Structure-activity relationship of novel DAPK inhibitors identified by structure-based virtual screening. Bioorg Med Chem18:2728-34 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Death-associated protein kinase 3 |
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| Name: | Death-associated protein kinase 3 |
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| Synonyms: | DAP kinase 3 | DAP-like kinase | DAPK3 | DAPK3_HUMAN | ZIP-kinase | ZIPK |
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| Type: | PROTEIN |
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| Mol. Mass.: | 52537.07 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_586564 |
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| Residue: | 454 |
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| Sequence: | MSTFRQEDVEDHYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREE
IEREVNILREIRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFL
KQILDGVHYLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGT
PEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEY
FSNTSELAKDFIRRLLVKDPKRRMTIAQSLEHSWIKAIRRRNVRGEDSGRKPERRRLKTT
RLKEYTIKSHSSLPPNNSYADFERFSKVLEEAAAAEEGLRELQRSRRLCHEDVEALAAIY
EEKEAWYREESDSLGQDLRRLRQELLKTEALKRQAQEEAKGALLGTSGLKRRFSRLENRY
EALAKQVASEMRFVQDLVRALEQEKLQGVECGLR
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| BDBM50314664 |
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| n/a |
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| Name | BDBM50314664 |
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| Synonyms: | 2-(2-chloro-5-iodophenyl)-4-(pyridin-4-ylmethylene)oxazol-5(4H)-one | CHEMBL1091784 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H8ClIN2O2 |
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| Mol. Mass. | 410.594 |
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| SMILES | Clc1ccc(I)cc1C1=N\C(=C/c2ccncc2)C(=O)O1 |t:9| |
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| Structure | 
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