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TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1
LigandBDBM50314688
Substrate/Competitorn/a
Meas. Tech.ChEMBL_625852 (CHEMBL1109788)
Ki 2200±n/a nM
Citation Dong, LMarakovits, JHou, XGuo, CGreasley, SDagostino, EFerre, RJohnson, MCKraynov, EThomson, JPathak, VMurray, BW Structure-based design of novel human Pin1 inhibitors (II). Bioorg Med Chem Lett20:2210-4 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Name:Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Synonyms:PIN1 | PIN1_HUMAN | PPIase Pin1 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Type:PROTEIN
Mol. Mass.:18248.11
Organism:Homo sapiens (Human)
Description:ChEMBL_1502595
Residue:163
Sequence:
MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHL
LVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARG
DLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE
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BDBM50314688
n/a
NameBDBM50314688
Synonyms:(R)-2-(2-naphthamido)-3-(3,4-dichlorophenyl)propanoic acid | CHEMBL1093344
TypeSmall organic molecule
Emp. Form.C20H15Cl2NO3
Mol. Mass.388.244
SMILESOC(=O)[C@@H](Cc1ccc(Cl)c(Cl)c1)NC(=O)c1ccc2ccccc2c1 |r|
Structure
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