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TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1
LigandBDBM50314706
Substrate/Competitorn/a
Meas. Tech.ChEMBL_625852 (CHEMBL1109788)
Ki 890±n/a nM
Citation Dong, LMarakovits, JHou, XGuo, CGreasley, SDagostino, EFerre, RJohnson, MCKraynov, EThomson, JPathak, VMurray, BW Structure-based design of novel human Pin1 inhibitors (II). Bioorg Med Chem Lett20:2210-4 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Name:Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Synonyms:PIN1 | PIN1_HUMAN | PPIase Pin1 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Type:PROTEIN
Mol. Mass.:18248.11
Organism:Homo sapiens (Human)
Description:ChEMBL_1502595
Residue:163
Sequence:
MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHL
LVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARG
DLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE
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BDBM50314706
n/a
NameBDBM50314706
Synonyms:(R)-2-(2-naphthamido)-5-(3-fluorophenyl)pent-4-enoic acid | CHEMBL1090715
TypeSmall organic molecule
Emp. Form.C22H18FNO3
Mol. Mass.363.3816
SMILESOC(=O)[C@@H](C\C=C\c1cccc(F)c1)NC(=O)c1ccc2ccccc2c1 |r|
Structure
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