| Reaction Details |
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 | Report a problem with these data |
| Target | Melatonin receptor type 1A |
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| Ligand | BDBM50315170 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_624959 (CHEMBL1107082) |
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| Ki | 1840±n/a nM |
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| Citation |  Hu, Y; Ho, MK; Chan, KH; New, DC; Wong, YH Synthesis of substituted N-[3-(3-methoxyphenyl)propyl] amides as highly potent MT(2)-selective melatonin ligands. Bioorg Med Chem Lett20:2582-5 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melatonin receptor type 1A |
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| Name: | Melatonin receptor type 1A |
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| Synonyms: | MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A |
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| Type: | Enzyme |
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| Mol. Mass.: | 39392.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P48039 |
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| Residue: | 350 |
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| Sequence: | MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRN
AGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITG
IAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFA
QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM
FVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ
NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
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| BDBM50315170 |
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| n/a |
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| Name | BDBM50315170 |
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| Synonyms: | CHEMBL1091716 | N-(3-(5-methoxy-2-(pyridin-2-ylmethoxy)phenyl)propyl)acetamide |
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| Type | Small organic molecule |
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| Emp. Form. | C18H22N2O3 |
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| Mol. Mass. | 314.3789 |
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| SMILES | COc1ccc(OCc2ccccn2)c(CCCNC(C)=O)c1 |
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| Structure | 
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