Reaction Details |
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Target | Mycothiol S-conjugate amidase |
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Ligand | BDBM50134315 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_626858 (CHEMBL1110815) |
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IC50 | 50000±n/a nM |
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Citation | Watts, KR; Ratnam, J; Ang, KH; Tenney, K; Compton, JE; McKerrow, J; Crews, P Assessing the trypanocidal potential of natural and semi-synthetic diketopiperazines from two deep water marine-derived fungi. Bioorg Med Chem18:2566-74 (2010) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Mycothiol S-conjugate amidase |
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Name: | Mycothiol S-conjugate amidase |
Synonyms: | MCA_MYCTU | mca |
Type: | PROTEIN |
Mol. Mass.: | 32719.79 |
Organism: | Mycobacterium tuberculosis |
Description: | ChEMBL_626858 |
Residue: | 288 |
Sequence: | MSELRLMAVHAHPDDESSKGAATLARYADEGHRVLVVTLTGGERGEILNPAMDLPDVHGR
IAEIRRDEMTKAAEILGVEHTWLGFVDSGLPKGDLPPPLPDDCFARVPLEVSTEALVRVV
REFRPHVMTTYDENGGYPHPDHIRCHQVSVAAYEAAGDFCRFPDAGEPWTVSKLYYVHGF
LRERMQMLQDEFARHGQRGPFEQWLAYWDPDHDFLTSRVTTRVECSKYFSQRDDALRAHA
TQIDPNAEFFAAPLAWQERLWPTEEFELARSRIPARPPETELFAGIEP
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BDBM50134315 |
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n/a |
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Name | BDBM50134315 |
Synonyms: | 7-hydroxy-11-hydroxymethyl-12-methyl-14,15-dithia-9,12-diazatetracyclo[9.2.2.01,9.03,8]pentadeca-3,5-diene-10,13-dione | CHEMBL331627 | GLIOTOXIN |
Type | Small organic molecule |
Emp. Form. | C13H14N2O4S2 |
Mol. Mass. | 326.391 |
SMILES | CN1C(=O)[C@]23CC4=CC=C[C@H](O)[C@H]4N2C(=O)[C@@]1(CO)SS3 |r,c:8,t:6,THB:12:13:1.2:19.20,15:14:1.2:19.20| |
Structure |
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