| Reaction Details |
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 | Report a problem with these data |
| Target | 17-beta-hydroxysteroid dehydrogenase type 3 |
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| Ligand | BDBM50241208 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_624968 (CHEMBL1108824) |
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| IC50 | >100000±n/a nM |
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| Citation |  Hu, GX; Liang, G; Chu, Y; Li, X; Lian, QQ; Lin, H; He, Y; Huang, Y; Hardy, DO; Ge, RS Curcumin derivatives inhibit testicular 17beta-hydroxysteroid dehydrogenase 3. Bioorg Med Chem Lett20:2549-51 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 17-beta-hydroxysteroid dehydrogenase type 3 |
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| Name: | 17-beta-hydroxysteroid dehydrogenase type 3 |
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| Synonyms: | DHB3_RAT | Edh17b3 | Hsd17b3 | Testosterone 17-beta-dehydrogenase 3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 34235.73 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1510493 |
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| Residue: | 306 |
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| Sequence: | MEQFLLSVGLLVCLVCLVKCVRFSRYLFLSFCKALPGSFLRSMGQWAVITGAGDGIGKAY
SFELARHGLNVVLISRTLEKLQVISEEIERTTGSRVKVVQADFTREDIYDHIEEQLKGLE
IGVLVNNVGMLPNLLPSHFLSTSGESQSVIHCNITSVVKMTQLVLKHMESRRRGLILNIS
SGVGVRPWPLYSLYSASKAFVCTFSKALNVEYRDKGIIIQVLTPYSVSTPMTKYLNTSRV
TKTADEFVKESLKYVTIGAETCGCLAHEILAIILNLIPSRIFYSSTTQRFLLKQFSDYLK
SNISNR
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| BDBM50241208 |
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| n/a |
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| Name | BDBM50241208 |
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| Synonyms: | (2E,6E)-2,6-bis(3,4,5-trimethoxybenzylidene)cyclohexanone | 2,6-Bis-(3,4,5-trimethoxy-benzylidene)-cyclohexanone | 2,6-bis((3,4,5-trimethoxyphenyl)methylene)-cyclohexanone | 2,6-bis(3,4,5-trimethoxybenzylidene)cyclohexanone | 2,6-bis-(3,4,5-trimethoxyphenylmethylene)-cyclohexanone | CHEMBL387599 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H30O7 |
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| Mol. Mass. | 454.5122 |
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| SMILES | COc1cc(\C=C2/CCC\C(=C/c3cc(OC)c(OC)c(OC)c3)C2=O)cc(OC)c1OC |
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| Structure | 
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