Reaction Details |
| Report a problem with these data |
Target | 6,7-dimethyl-8-ribityllumazine synthase |
---|
Ligand | BDBM50316575 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEMBL_631473 (CHEMBL1114707) |
---|
Ki | >1000000±n/a nM |
---|
Citation | Talukdar, A; Morgunova, E; Duan, J; Meining, W; Foloppe, N; Nilsson, L; Bacher, A; Illarionov, B; Fischer, M; Ladenstein, R; Cushman, M Virtual screening, selection and development of a benzindolone structural scaffold for inhibition of lumazine synthase. Bioorg Med Chem18:3518-34 (2010) [PubMed] Article |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
6,7-dimethyl-8-ribityllumazine synthase |
---|
Name: | 6,7-dimethyl-8-ribityllumazine synthase |
Synonyms: | RISB_MYCTU | ribH |
Type: | PROTEIN |
Mol. Mass.: | 16367.39 |
Organism: | Mycobacterium tuberculosis |
Description: | ChEMBL_631469 |
Residue: | 160 |
Sequence: | MKGGAGVPDLPSLDASGVRLAIVASSWHGKICDALLDGARKVAAGCGLDDPTVVRVLGAI
EIPVVAQELARNHDAVVALGVVIRGQTPHFDYVCDAVTQGLTRVSLDSSTPIANGVLTTN
TEEQALDRAGLPTSAEDKGAQATVAALATALTLRELRAHS
|
|
|
BDBM50316575 |
---|
n/a |
---|
Name | BDBM50316575 |
Synonyms: | CHEMBL1095229 | Ethyl2-(6-chloro-2,4,dioxo-1,2,3,4-tetrahydropyrimidin-5-ylamino)-2-oxoethanoate |
Type | Small organic molecule |
Emp. Form. | C8H8ClN3O5 |
Mol. Mass. | 261.619 |
SMILES | CCOC(=O)C(=O)Nc1c(Cl)[nH]c(=O)[nH]c1=O |
Structure |
|