Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
Target6,7-dimethyl-8-ribityllumazine synthase
LigandBDBM50316575
Substrate/Competitorn/a
Meas. Tech.ChEMBL_631473 (CHEMBL1114707)
Ki>1000000±n/a nM
Citation Talukdar, AMorgunova, EDuan, JMeining, WFoloppe, NNilsson, LBacher, AIllarionov, BFischer, MLadenstein, RCushman, M Virtual screening, selection and development of a benzindolone structural scaffold for inhibition of lumazine synthase. Bioorg Med Chem18:3518-34 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
6,7-dimethyl-8-ribityllumazine synthase
Name:6,7-dimethyl-8-ribityllumazine synthase
Synonyms:RISB_MYCTU | ribH
Type:PROTEIN
Mol. Mass.:16367.39
Organism:Mycobacterium tuberculosis
Description:ChEMBL_631469
Residue:160
Sequence:
MKGGAGVPDLPSLDASGVRLAIVASSWHGKICDALLDGARKVAAGCGLDDPTVVRVLGAI
EIPVVAQELARNHDAVVALGVVIRGQTPHFDYVCDAVTQGLTRVSLDSSTPIANGVLTTN
TEEQALDRAGLPTSAEDKGAQATVAALATALTLRELRAHS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50316575
n/a
NameBDBM50316575
Synonyms:CHEMBL1095229 | Ethyl2-(6-chloro-2,4,dioxo-1,2,3,4-tetrahydropyrimidin-5-ylamino)-2-oxoethanoate
TypeSmall organic molecule
Emp. Form.C8H8ClN3O5
Mol. Mass.261.619
SMILESCCOC(=O)C(=O)Nc1c(Cl)[nH]c(=O)[nH]c1=O
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: