Reaction Details |
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Target | 6,7-dimethyl-8-ribityllumazine synthase |
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Ligand | BDBM50316576 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_631472 (CHEMBL1114706) |
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Ki | 832000±n/a nM |
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Citation | Talukdar, A; Morgunova, E; Duan, J; Meining, W; Foloppe, N; Nilsson, L; Bacher, A; Illarionov, B; Fischer, M; Ladenstein, R; Cushman, M Virtual screening, selection and development of a benzindolone structural scaffold for inhibition of lumazine synthase. Bioorg Med Chem18:3518-34 (2010) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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6,7-dimethyl-8-ribityllumazine synthase |
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Name: | 6,7-dimethyl-8-ribityllumazine synthase |
Synonyms: | RISB_MYCTU | ribH |
Type: | PROTEIN |
Mol. Mass.: | 16367.39 |
Organism: | Mycobacterium tuberculosis |
Description: | ChEMBL_631469 |
Residue: | 160 |
Sequence: | MKGGAGVPDLPSLDASGVRLAIVASSWHGKICDALLDGARKVAAGCGLDDPTVVRVLGAI
EIPVVAQELARNHDAVVALGVVIRGQTPHFDYVCDAVTQGLTRVSLDSSTPIANGVLTTN
TEEQALDRAGLPTSAEDKGAQATVAALATALTLRELRAHS
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BDBM50316576 |
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n/a |
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Name | BDBM50316576 |
Synonyms: | 1,1-difluoro-5-(2-oxo-1,2-dihydrobenzo[cd]indole-6-sulfonamido)pentylphosphonic acid | CHEMBL1096338 |
Type | Small organic molecule |
Emp. Form. | C16H17F2N2O6PS |
Mol. Mass. | 434.352 |
SMILES | OP(O)(=O)C(F)(F)CCCCNS(=O)(=O)c1ccc2NC(=O)c3cccc1c23 |
Structure |
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