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TargetArginase-1
LigandBDBM50316603
Substrate/Competitorn/a
Meas. Tech.ChEMBL_631783
Ki 4000±n/a nM
Citation Ilies MDi Costanzo LNorth MLScott JAChristianson DW 2-aminoimidazole amino acids as inhibitors of the binuclear manganese metalloenzyme human arginase I. J Med Chem 53:4266-76 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Arginase-1
Name:Arginase-1
Synonyms:ARG1 | Liver-type arginase | Type I arginase
Type:PROTEIN
Mol. Mass.:34737.53
Organism:Homo sapiens (Human)
Description:ChEMBL_978893
Residue:322
Sequence:
MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPN
DSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGV
IWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLR
DVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSF
TPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAIT
LACFGLAREGNHKPIDYLNPPK
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  Blast E-value cutoff:
BDBM50316603
n/a
NameBDBM50316603
Synonyms:2-(S)-amino-5-(2-aminoimidazol-1-yl)pentanoic acid | CHEMBL1099169
TypeSmall organic molecule
Emp. Form.C8H14N4O2
Mol. Mass.198.2224
SMILESN[C@@H](CCCn1ccnc1N)C(O)=O |r|
Structure
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