| Reaction Details |
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 | Report a problem with these data |
| Target | Arginase-1 |
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| Ligand | BDBM50316608 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_631783 (CHEMBL1108176) |
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| Ki | 3600000±n/a nM |
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| Citation |  Ilies, M; Di Costanzo, L; North, ML; Scott, JA; Christianson, DW 2-aminoimidazole amino acids as inhibitors of the binuclear manganese metalloenzyme human arginase I. J Med Chem53:4266-76 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Arginase-1 |
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| Name: | Arginase-1 |
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| Synonyms: | ARG1 | ARGI1_HUMAN | Liver-type arginase | Type I arginase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 34737.53 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_978893 |
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| Residue: | 322 |
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| Sequence: | MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPN
DSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGV
IWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLR
DVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSF
TPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAIT
LACFGLAREGNHKPIDYLNPPK
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| BDBM50316608 |
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| n/a |
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| Name | BDBM50316608 |
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| Synonyms: | 1H-Imidazol-2-yl-ammonium | 1H-Imidazol-2-ylamine | 1H-imidazol-2-amine | 2-Aminoimidazole | CHEMBL2392115 | CHEMBL291627 |
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| Type | Small organic molecule |
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| Emp. Form. | C3H5N3 |
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| Mol. Mass. | 83.0919 |
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| SMILES | Nc1ncc[nH]1 |
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| Structure | 
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