| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50317010 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_630131 (CHEMBL1113722) |
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| Ki | 3.2±n/a nM |
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| Citation |  Shook, BC; Rassnick, S; Hall, D; Rupert, KC; Heintzelman, GR; Hansen, K; Chakravarty, D; Bullington, JL; Scannevin, RH; Magliaro, B; Westover, L; Carroll, K; Lampron, L; Russell, R; Branum, S; Wells, K; Damon, S; Youells, S; Li, X; Osbourne, M; Demarest, K; Tang, Y; Rhodes, K; Jackson, PF Methylene amine substituted arylindenopyrimidines as potent adenosine A(2A)/A(1) antagonists. Bioorg Med Chem Lett20:2864-7 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36520.92 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30542 |
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| Residue: | 326 |
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| Sequence: | MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPAPPIDEDLPEERPDD
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| BDBM50317010 |
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| n/a |
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| Name | BDBM50317010 |
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| Synonyms: | 2-amino-4-(thiophen-2-yl)-5H-indeno[1,2-d]pyrimidin-5-one | CHEMBL1086846 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H9N3OS |
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| Mol. Mass. | 279.316 |
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| SMILES | Nc1nc2-c3ccccc3C(=O)c2c(n1)-c1cccs1 |
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| Structure | 
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