| Reaction Details |
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 | Report a problem with these data |
| Target | Thymidine kinase |
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| Ligand | BDBM50314837 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_632671 (CHEMBL1112809) |
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| IC50 | 73000±n/a nM |
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| Citation |  Lin, J; Roy, V; Wang, L; You, L; Agrofoglio, LA; Deville-Bonne, D; McBrayer, TR; Coats, SJ; Schinazi, RF; Eriksson, S 3'-(1,2,3-Triazol-1-yl)-3'-deoxythymidine analogs as substrates for human and Ureaplasma parvum thymidine kinase for structure-activity investigations. Bioorg Med Chem18:3261-9 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Thymidine kinase |
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| Name: | Thymidine kinase |
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| Synonyms: | KITH_UREPA | tdk |
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| Type: | PROTEIN |
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| Mol. Mass.: | 25374.94 |
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| Organism: | Ureaplasma parvum |
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| Description: | ChEMBL_632671 |
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| Residue: | 223 |
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| Sequence: | MAKVNAFSKKIGWIELITGPMFAGKTAELIRRLHRLEYADVKYLVFKPKIDTRSIRNIQS
RTGTSLPSVEVESAPEILNYIMSNSFNDETKVIGIDEVQFFDDRICEVANILAENGFVVI
ISGLDKNFKGEPFGPIAKLFTYADKITKLTAICNECGAEATHSLRKIDGKHADYNDDIVK
IGCQEFYSAVCRHHHKVPNRPYLNSNSEEFIKFFKNKKRNKNI
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| BDBM50314837 |
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| n/a |
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| Name | BDBM50314837 |
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| Synonyms: | 3'-(4-Benzyl-1,2,3-triazol-1-yl)-3'-deoxy-beta-D-thymidine | 3'-(4-Benzyl-1,2,3-triazol-1-yl)-3'-deoxythymidine | CHEMBL1090133 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H21N5O4 |
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| Mol. Mass. | 383.4011 |
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| SMILES | Cc1cn([C@H]2C[C@@H]([C@@H](CO)O2)n2cc(Cc3ccccc3)nn2)c(=O)[nH]c1=O |r| |
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| Structure | 
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