| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Aldo-keto reductase family 1 member B1 [K65Q] |
|---|
| Ligand | BDBM50318060 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_631366 (CHEMBL1109118) |
|---|
| IC50 | 420±n/a nM |
|---|
| Citation |  Zou, XQ; Peng, SM; Hu, CP; Tan, LF; Yuan, Q; Deng, HW; Li, YJ Synthesis, characterization and vasculoprotective effects of nitric oxide-donating derivatives of chrysin. Bioorg Med Chem18:3020-5 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Aldo-keto reductase family 1 member B1 [K65Q] |
|---|
| Name: | Aldo-keto reductase family 1 member B1 [K65Q] |
|---|
| Synonyms: | AKR1B1 | ALDR_BOVIN | Aldose reductase |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 35916.27 |
|---|
| Organism: | Bos taurus (Cattle) |
|---|
| Description: | P16116[K65Q] |
|---|
| Residue: | 315 |
|---|
| Sequence: | AHNIVLYTGAKMPILGLGTWKSPPGKVTEAVKVAIDLGYRHIDCAHVYQNENEVGLALQA
KLQEQVVKREDLFIVSKLWCTYHDKDLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKD
FFPLDEDGNVIPSEKDFVDTWTAMEELVDEGLVKAIGVSNFNHLQVEKILNKPGLKYKPA
VNQIECHPYLTQEKLIQYCNSKGIVVTAYSPLGSPDRPWAKPEDPSILEDPRIKAIADKY
NKTTAQVLIRFPIQRNLIVIPKSVTPERIAENFQVFDFELDKEDMNTLLSYNRDWRACAL
VSCASHRDYPFHEEF
|
|
|
|---|
| BDBM50318060 |
|---|
| n/a |
|---|
| Name | BDBM50318060 |
|---|
| Synonyms: | 7-(6-(nitrooxy)hexyloxy)-4-oxo-2-phenyl-4H-chromen-5-yl acetate | CHEMBL1096050 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H23NO8 |
|---|
| Mol. Mass. | 441.4306 |
|---|
| SMILES | CC(=O)Oc1cc(OCCCCCCO[N+]([O-])=O)cc2oc(cc(=O)c12)-c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
