| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
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| Ligand | BDBM50151720 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_632379 (CHEMBL1115584) |
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| Ki | 23±n/a nM |
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| Citation |  Baur, F; Beattie, D; Beer, D; Bentley, D; Bradley, M; Bruce, I; Charlton, SJ; Cuenoud, B; Ernst, R; Fairhurst, RA; Faller, B; Farr, D; Keller, T; Fozard, JR; Fullerton, J; Garman, S; Hatto, J; Hayden, C; He, H; Howes, C; Janus, D; Jiang, Z; Lewis, C; Loeuillet-Ritzler, F; Moser, H; Reilly, J; Steward, A; Sykes, D; Tedaldi, L; Trifilieff, A; Tweed, M; Watson, S; Wissler, E; Wyss, D The identification of indacaterol as an ultralong-acting inhaled beta2-adrenoceptor agonist. J Med Chem53:3675-84 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-2 adrenergic receptor |
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| Name: | Beta-2 adrenergic receptor |
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| Synonyms: | ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor |
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| Type: | n/a |
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| Mol. Mass.: | 46461.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07550 |
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| Residue: | 413 |
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| Sequence: | MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
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| BDBM50151720 |
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| n/a |
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| Name | BDBM50151720 |
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| Synonyms: | ARFORMOTEROL TARTRATE | CHEMBL1363 | CHEMBL605993 | FORMOTEROL | FORMOTEROL FUMARATE | Foradil | N-(2-Hydroxy-5-{1-hydroxy-2-[2-(4-methoxy-phenyl)-1-methyl-ethylamino]-ethyl}-phenyl)-formamide | N-(2-hydroxy-5-((R)-1-hydroxy-2-((R)-1-(4-methoxyphenyl)propan-2-ylamino)ethyl)phenyl)formamide | Symbicort | cid_9912089 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H24N2O4 |
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| Mol. Mass. | 344.4049 |
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| SMILES | COc1ccc(C[C@@H](C)NC[C@H](O)c2ccc(O)c(NC=O)c2)cc1 |r| |
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| Structure | 
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