| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin K |
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| Ligand | BDBM50318880 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_633322 (CHEMBL1120161) |
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| IC50 | 58±n/a nM |
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| Citation |  Allen, JG; Fotsch, C; Babij, P Emerging targets in osteoporosis disease modification. J Med Chem53:4332-53 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cathepsin K |
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| Name: | Cathepsin K |
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| Synonyms: | CATK_RAT | Ctsk |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36798.82 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_633322 |
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| Residue: | 329 |
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| Sequence: | MWVFKFLLLPVVSFALSPEETLDTQWELWKKTHGKQYNSKVDEISRRLIWEKNLKKISVH
NLEASLGAHTYELAMNHLGDMTSEEVVQKMTGLRVPPSRSFSNDTLYTPEWEGRVPDSID
YRKKGYVTPVKNQGQCGSCWAFSSAGALEGQLKKKTGKLLALSPQNLVDCVSENYGCGGG
YMTTAFQYVQQNGGIDSEDAYPYVGQDESCMYNATAKAAKCRGYREIPVGNEKALKRAVA
RVGPVSVSIDASLTSFQFYSRGVYYDENCDRDNVNHAVLVVGYGTQKGNKYWIIKNSWGE
SWGNKGYVLLARNKNNACGITNLASFPKM
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| BDBM50318880 |
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| n/a |
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| Name | BDBM50318880 |
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| Synonyms: | (S)-2-(4-(2-(1-(biphenyl-3-ylamino)cyclohexanecarboxamido)butylamino)phenoxy)acetic acid | CHEMBL1083675 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H37N3O4 |
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| Mol. Mass. | 515.6432 |
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| SMILES | CC[C@@H](CNc1ccc(OCC(O)=O)cc1)NC(=O)C1(CCCCC1)Nc1cccc(c1)-c1ccccc1 |r| |
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| Structure | 
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