| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
|---|
| Ligand | BDBM50318992 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_635468 (CHEMBL1120618) |
|---|
| Ki | 80±n/a nM |
|---|
| Citation |  Tasler, S; Baumgartner, R; Aschenbrenner, A; Ammendola, A; Wolf, K; Wieber, T; Schachtner, J; Blisse, M; Quotschalla, U; Ney, P A vHTS approach for the identification of beta-adrenoceptor ligands. Bioorg Med Chem Lett20:3399-404 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Beta-2 adrenergic receptor |
|---|
| Name: | Beta-2 adrenergic receptor |
|---|
| Synonyms: | ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor |
|---|
| Type: | n/a |
|---|
| Mol. Mass.: | 46461.69 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P07550 |
|---|
| Residue: | 413 |
|---|
| Sequence: | MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
|
|
|
|---|
| BDBM50318992 |
|---|
| n/a |
|---|
| Name | BDBM50318992 |
|---|
| Synonyms: | 2-((1-(3-(2-allylphenoxy)-2-hydroxypropyl)piperidin-4-yl)methyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione | CHEMBL1086005 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C30H32N2O4 |
|---|
| Mol. Mass. | 484.5861 |
|---|
| SMILES | OC(COc1ccccc1CC=C)CN1CCC(CN2C(=O)c3cccc4cccc(C2=O)c34)CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
