| Reaction Details |
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 | Report a problem with these data |
| Target | Peroxisome proliferator-activated receptor alpha |
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| Ligand | BDBM50319270 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_633996 (CHEMBL1117969) |
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| EC50 | 600±n/a nM |
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| Citation |  Urbahns, K; Woltering, M; Nikolic, S; Pernerstorfer, J; Bischoff, H; Dittrich-Wengenroth, E; Lustig, K Glycine amides as PPARalpha agonists. Bioorg Med Chem Lett20:3376-9 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Peroxisome proliferator-activated receptor alpha |
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| Name: | Peroxisome proliferator-activated receptor alpha |
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| Synonyms: | NR1C1 | Nuclear receptor subfamily 1 group C member 1 | PPAR | PPAR alpha/gamma | PPAR-alpha | PPARA | PPARA_HUMAN | Peroxisome Proliferator-Activated Receptor alpha | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor alpha (PPAR alpha) |
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| Type: | Enzyme |
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| Mol. Mass.: | 52222.08 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q07869 |
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| Residue: | 468 |
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| Sequence: | MVDTESPLCPLSPLEAGDLESPLSEEFLQEMGNIQEISQSIGEDSSGSFGFTEYQYLGSC
PGSDGSVITDTLSPASSPSSVTYPVVPGSVDESPSGALNIECRICGDKASGYHYGVHACE
GCKGFFRRTIRLKLVYDKCDRSCKIQKKNRNKCQYCRFHKCLSVGMSHNAIRFGRMPRSE
KAKLKAEILTCEHDIEDSETADLKSLAKRIYEAYLKNFNMNKVKARVILSGKASNNPPFV
IHDMETLCMAEKTLVAKLVANGIQNKEAEVRIFHCCQCTSVETVTELTEFAKAIPGFANL
DLNDQVTLLKYGVYEAIFAMLSSVMNKDGMLVAYGNGFITREFLKSLRKPFCDIMEPKFD
FAMKFNALELDDSDISLFVAAIICCGDRPGLLNVGHIEKMQEGIVHVLRLHLQSNHPDDI
FLFPKLLQKMADLRQLVTEHAQLVQIIKKTESDAALHPLLQEIYRDMY
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| BDBM50319270 |
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| n/a |
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| Name | BDBM50319270 |
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| Synonyms: | 2-(4-(((2-(2,5-dimethylphenylamino)-2-oxoethyl)(furan-2-ylmethyl)amino)methyl)phenoxy)-2-methylpropanoic acid | CHEMBL1084320 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H30N2O5 |
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| Mol. Mass. | 450.5268 |
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| SMILES | Cc1ccc(C)c(NC(=O)CN(Cc2ccco2)Cc2ccc(OC(C)(C)C(O)=O)cc2)c1 |
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| Structure | 
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